Reproduction Abstracts

Polycystic ovary syndrome (PCOS) affects over 5% of women of reproductive age. It is associated with an ovulatory infertility, menstrual disturbances as well as metabolic abnormalities including obesity and insulin resistance. PCOS has a strong genetic basis but studies of ovarian gene expression in PCOS are limited by the difficulty in obtaining tissue samples from women with and without PCOS. For that reason, most studies have been performed in granulosa–lutein (GL) cel...